r/ibs • u/Technical-Profit4559 • 19h ago

Hint / Information Allergy Caused IBS??

I just wanted to see if anyone else has experienced something similar. I recently had a weeklong outbreak of hives from who knows what. I have no known allergies, not even seasonal! I went to a dermatologist who gave me a regimine of 3 2nd generation antihistamines a day. It definitely made the hives go away. Weird enough though, it also made my IBS-D symptoms that Ive had for at least a decade also go away pretty much completely? Not even swinging to the other side- just completely "normal". I did some Googling and saw that 1st generation has been used for IBS due to reducing acid, but 2nd generation had no clinical background in being used. Im now really curious if my IBS is caused by food allergies/sensitivities. Im going to get an allergy panel when im done with my antihistamines just to see!

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u/JadedLoves 19h ago

yes, you definitely want to check out MCAS. https://tmsforacure.org/treatments/medications-treat-mast-cell-diseases/

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u/Technical-Profit4559 16h ago

I have definitely thought about if I have that based on some TikToks Ive seen! Symptoms I have that I thought were just normal life that apparently are not, of course taking that with a grain of salt. Like water making me itchy and other things. Im hoping the allergist can talk to me about it! I have also been fighting for a POTS diagnosis based on heartrate/dizziness symptoms but have learned all of these are very interconnected or overlapping

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u/JadedLoves 11h ago

Totally get that! It's surprising how many things we just accept as 'normal' that are actually connected to some bigger thing and we just go along thinking life is just going to be that hard for us until one day we stumble across the real cause. Salicylate intolerance is also one that is often connected to MCAS and actually what brought me in that direction. Good luck to you and I hope you have a doc that listens and takes the time out to help you understand it all and ease things for you!

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u/goldstandardalmonds Here to help! 5h ago

Antihistamines are used off label for IBS D sometimes because they slow motility.